
QUÉ ES DIGNA BIOTECH

Publicaciones científicas de la Dra. María Eugenia Cornet
- Herrero, C., Cornet, M. E., Lopez, C., García-Barreno, P., Municio, M. M., Moscat, J.: Ca2+-induced changes in the secondary structure of a 60-kDa Phosphoinositide-Specific Phospholipase C from Bovine Brain Cytosol. Biochem. J. 255, 807-812, 1988.
- Díaz-Meco, M. T., Larrodera, P., Lopez-Barahona, M., Cornet, M. E., Moscat, J.: Phospholipase C-Mediated Hydrolysis of Phosphatidilcholine is Activated by Muscarinic Agonists. Biochem. J. 263, 115-12, 1989.
- Moscat, J., Cornet, M. E., Díaz-Meco, M. T., Larrodera, P., Lopez-Alanon, D., Lopez-Barahona, M.: Activation of phosphatidylcholine-specific phospholipase C in cell growth and oncogene transformation. Biochem. Soc. Trans., 17 (6), 988-91, 1989.
- Diaz-Laviada I., Larrodera, P., Díaz-Meco M. T., Cornet, M. E., Guddal, P. H., Johansen T.,
Moscat, J.: Evidence for a role of phosphatidylcholine-hydrolysing phospholipase C in the regulation of protein kinase C by ras and src oncogenes. EMBO J. 9 (12), 3907-12, 1990.
- Lopez-Barahona, M., Kaplan, Paul L., Cornet, M. E., Larrodera, P., Díaz-Meco, M. T., Moscat, J.: Kinetic evidence of a rapid activation of phosphatidilcholine hydrolysis by Ki-ras oncogene: Possible involvement in late steps of the mitogenic cascade. J. Biol. Chem. 265, 9022-9026, 1990.
- Larrodera, P., Cornet, M. E., Díaz-Meco, M. T., Lopez-Barahona, M., Díaz-Laviada, I., Guddal, P. H., Johansen, T., Moscat, J.: Phospholipase C mediated hydrolysis of phosphatidilcholine is an important step in PDGF-stimulated DNA synthesis. Cell 61, 1113-1120, 1990.
- Díaz-Laviada, I., Larrodera, P., Nieto, J. L., Cornet, M. E., Díaz-Meco, M. T., Sanchez, M. J., Guddal, P. H., Johansen, T., Haro, A., Moscat, J.: Mechanism of inhibition of adenylate cyclase by phospholipase C-catalyzed hydrolysis of phosphatidylcholine. Involvement of a pertussis toxin-sensitive G protein and protein kinase C. J. Biol. Chem. 266(2), 1170-6, 1991.
- García de Herreros, A., Dominguez, I., Díaz-Meco, M. T., Cornet, M. E., Graziani, G., Guddal, P. H., Johansen, T., Moscat, J.: Requirement of phospholipase C-hydrolysis of phosphatidylcholine for maturation of Xenopus laevis oocytes in response to insulin and ras p21. J. Biol. Chem. 266, 6825-6829, 1991.
- Domínguez, I., Marshall, M. S., Gibbs, J. B., García de Herreros, A., Cornet, M. E., Graziani, G., Díaz-Meco, M. T., Johansen, T., Mc Cormick, F., Moscat, J.: Role of GTPase activating protein and protein kinase C in mitogenic signalling through phosphatidylcholine hydrolyzing phospholipase C. EMBO J. 10, 3215-3220, 1991.
- Díaz-Meco, M. T., Domínguez, I., Sanz, L., Municio, M. M., Berra, E., Cornet, M. E., Moscat, J.: Phospholipase C-mediated hydrolysis of phosphatidilcholine is a target of TGF- 1 inhibitory signals. Mol. Cell. Biol. 12, 302-308, 1992.
- Domínguez, I., Díaz-Meco, M. T., Municio, M. M., Berra, E., García de Herreros, A., Cornet, M. E., Sanz, L., Moscat, J.: Evidence for a Role of Protein Kinase C Z subspecie in Maturation of Xenopus laevis Oocytes. Mol. Cell. Biol. 12, 3776-3783, 1992.
- Martínez-Martín, P., Raffaelli, E., Titus, F., Despuig, J., Fragoso, Y. D., Díez Tejedor, E., Liaño, H., Leira, R., Cornet, M. E., van Toor, B. S. J., Cámara, J., Peil, H., Vix, J. M., Ortiz, P., Cooperative Study Group: Efficacy and safety of metamizol versus acetylsalicylic acid in patients with moderate episodic tension-type headache: a randomised, double-blind, placebo- and active-controlled, multicentre study. Cephalalgia 21, 604-610, 2001.
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