Ir a contenido.

Digna Biotech
Inicio > Qué es Digna Biotech > Organización > Equipo humano > Dr. Pablo Ortiz

Publicaciones científicas del Dr. Pablo Ortiz

  1. Cabrero, C.; Mérida, I.; Ortiz, P.; Varela, I.; Mato, J. M.: Effects of alloxan on S- Adenosylmethionine metabolism in the rat liver. Biochem. Pharmacol. 35 (13), 2261-2264, 1986.
  2. Martín-Duce, A.; Ortiz, P.; Cabrero, C.; Mato, J. M.: S-Adenosyl-L-Methionine synthetase and phospholipid methyltransferase are inhibited in human cirrhosis. Hepatology 8 (1), 65-68, 1988.
  3. Cabrero, C.; Martín-Duce, A.; Ortiz, P.; Alemany, S.; Mato, J. M.: Specific loss of the high-molecular-weight form of S-Adenosyl-L-Methionine synthetase in human liver cirrhosis. Hepatology 8 (6), 1530-1534, 1988.
  4. Corrales, F.; Cabrero, C.; Pajares, M. A.; Ortiz, P.; Martín-Duce, A.; Mato, J. M.: Inactivation and dissociation of S-Adenosylmethionine synthetase by modification of sulphydryl groups and its possible occurrence in liver cirrhosis. Hepatology 11 (2), 216-222, 1990.
  5. Mato, J. M.; Corrales, F.; Martín-Duce, A.; Ortiz, P.; Pajares, M. A.; Cabrero, C.: Mechanisms and consequences of the impairment of the transulfuration pathway in liver disease. Drugs 40 (suppl. 3), 58-64, 1990.
  6. Caballero Plasencia, A. M.; Montero García, M.; Ceallos Torres, A.; Ortiz Betés, P.; Bortolini, M.: Total parenteral nutrition plus S-Adenosylmethionine in a case of intrahepatic cholestasis. Drugs Invest 3 (5), 333-335, 1991.
  7. Mateu, M.; Ortiz, P.; Bellod, P.: The efficacy and tolerance of minor analgesics in slight thoracic trauma. Curr. Ther. Res. 51 (4), 626-633, 1992.
  8. Corrales, F.; Alvarez, L.; Pajares, M. A.; Ortiz, P.; Mato, J. M.: Impairment of methionine metabolism in liver disease. Drugs Investigation (suppl. 4), 8-13, 1992.
  9. Ortiz, P.; Moreno, J.; Puerta, J. L.; Mato, J. M.: S-Adenoyl-L-Methionine and the Liver. Italian J. of Gastroenterology 25, 64-66, 1993.
  10. Muriel, C.; Ortiz, P. and the Cooperative Study Group: Efficacy of two different intramuscular doses of dipyrone in renal colic. Methods and Findings in Experimental and Clinical Pharmacology 15, 465-469, 1993.
  11. Rodríguez, M.; Rull, M.; Barutell, C.; Gálvez, R.; Pallarés, J.; Vidal, F.; Aliaga, L.; Moreno, J.; Puerta, J. L.; Ortiz, P.: Efficacy and tolerance of oral dipyrone versus oral morphine in cancer pain. European Journal of Cancer 30, 584-587, 1994.
  12. Vara, E.; Arias-Díaz, J.; García, C.; Villa, N.; Simón, C.; Ortiz, P.; Balibrea, J. L.: S-Adenosyl-Methionine might protect transplanted hepatocytes against the toxic effects of cytokines. Transplantation Proceedings 26 (6), 3363-3365, 1994.
  13. Vara, E.; Arias-Díaz, J.; Villa, N.; Hernández, J.; García, C.; Ortiz, P.; Balibrea, J. L.: Beneficial effect of S-Adenosylmethionine during both Cold Storage and Cryopreservation of Isolated Hepatocytes. Cryobiology 32, 422-427, 1995.
  14. Muriel-Villoria, C.; Zungri-Telo, E.; Díaz-Curiel, M.; Fernández-Guerrero, M.; Moreno, J.; Puerta, J.; Ortiz, P.: Comparison of the onset and duration of the analgesic effect of dipyrone, 1 or 2 g, by the intramuscular or intravenous route, in acute renal colic. Eur. J. Clin. Pharmacol. 48, 103-107, 1995.
  15. Arias-Díaz, J.; Vara, E.; García, C.; Villa, N.; Rodríguez, J. M.; Ortiz, P.; Balibrea, J. L.: S-Adenosyl-methionine protects hepatocytes against the effects of cytokines. Journal of Surgical Research 62, 79-84, 1996.
  16. Mato, J. M.; Ortiz, P.: Metabolism of Methionine in liver disease. Meth. Find. Exp. Clin. Pharmacol. 18 (suppl. B), 35-46, 1996.
  17. Mato, J. M.; Alvarez, P.; Ortiz, P.; Pajares, M. A.: S-Adenosylmethionine synthesis: Molecular mechanisms and clinical implications. Pharmacol. Ther. 73 (3), 265-280, 1997.
  18. Martín-Duce, A.; Moreno, J.; Puerta, J.; Ortiz, P.: Effetiveness of metamizol in the management of pain after abdominal surgery: Comparison of 1 or 2 g by the intramuscular or intravenous route. The Pain Clinic 10 (1), 27-34, 1997.
  19. González-Correa, J. A.; De la Cruz, J. P.; Martín-Aurioles, E.; López-Egea, M. A.; Ortiz, P.; Sánchez de la Cuesta, F.: Effects of S-Adenosyl-L-Methionine on hepatic and renal oxidative stress in an experimental model of acute biliary obstruction in rats. Hepatology 26 (1), 121-127, 1997.
  20. De la Cruz, J. P.; Mérida, M.; González-Correa, J. A.; Ortiz, P.; Sánchez de la Cuesta, F.: Effects of S-Adenosyl-L-Methionine on Blood Platelet Activation. Gen. Pharmac. 29 (4), 651-655, 1997.
  21. De la Cruz, J. P.; González-Correa, J. A.; Martín-Aurioles, E.; Ortiz, P.; Sánchez de la Cuesta, F.: Effects of S-adenosyl-L-methionine on Platelet Thromboxane and Vascular Prostacyclin. Biochem. Pharmacol. 53, 1761-1763, 1997.
  22. Planas, M. E.; Gay Escoda, C.; Bagan, J. V.; Santamaría, J.; Peñarrocha, M.; Donado, M.; Puerta, J. L.; G. Magaz, I.; Ruiz, J.; Moreno, J.; Ortiz, P.: Oral Metamizol (1 and 2 g) versus Ibuprofen and Placebo in the treatment of lower third molar surgery pain: Randomized double-blind multicenter study. Eur. J. Clin. Pharmacol. 53, 405-409, 1998.
  23. Campos, C.; de Gregorio, R.; García-Nieto, R.; Gago, F.; Ortiz, P.; Alemany, S.: Regulation of cyclooxygenase activity by metamizol. Eur. J. of Pharmacol. 378, 339-347, 1999.
  24. Mato, J. M.; Cámara, J.; Fernández de Paz, J.; Caballería, L.; Coll, S.; Caballero, A.; García-Buey, L.; Beltrán, J.; Benita, V.; Caballería, J.; Solà, R.; Moreno-Otero, R.; Barrao, F.; Martín-Duce, A.; Correa, J. A.; Parés, A.; Barrao, E.; García-Magaz, I.; Puerta, J. L.; Moreno, J.; Boissard, G.; Ortiz, P.; Rodés, J.: S-Adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial. J. of Hepatology 30, 1081-1089, 1999.
  25. Villalobos, M. A.; De la Cruz, J. P.; Cuerda, M. A.; Ortiz, P.; Smith-Agreda, J. M.; Sánchez de la Cuesta, F.: Effect of S-adenosyl-L-methionine on rat brain oxidative stress damage in a combined model of permanent focal ischemia and global ischemia-reperfusion. Brain Research 883, 31-40, 2000.
  26. Martinez-Martín, P.; Raffaelli, E.; Titus, F.; Despuig, J.; Fragoso, Y. D.; Díez Tejedor, E.; Liaño, H.; Leira, R.; Cornet, M. E.; van Toor, B. S. J.; Cámara, J.; Peil, H.; Vix, J. M.; Ortiz, P.; Cooperative Study Group: Efficacy and safety of metamizol versus acetylsalicylic acid in patients with moderate episodic tension-type headache: a randomised, double-blind, placebo- and active-controlled, multicentre study. Cephalalgia 21, 604-610, 2001.
  27. Torres, L. M.; Rodríguez, M. J.; Montero, A., Herrera, J.; Calderón, E.; Cabrera, J.; Porres, R.; De la Torre, M. R.; Martínez, T.; Gómez, J. L.; Ruiz, J.; García-Magaz, I.; Cámara, J.; Ortiz, P.: Efficacy and safety of dipyrone versus tramadol in the Management of pain after hysterectomy: a randomized, double-blind, multicenter study. Regional Anesthesia and Pain Medicine 26 (2), 119-124, 2001.
  28. Artaza, M. A.; Puerta, J. L.; Ortiz, P.; Laporte, J. R.: Bioavailability of two metamizole (dipyrone) solutions as single doses of 2 g versus metamizole capsules. International Journal of Clinical Pharmacology and Therapeutics 40 (7), 322-326, 2002.

<< Volver

Organización
© Digna Biotech · Información Legal Subir